Ph.D. in Immuno-oncology and Virology (in progress)
Tel Aviv, Israel 🇮🇱
Sucheta De
Immuno-oncology & Virology
Ph.D. candidate in Immuno-oncology and Virology focused on how signal transduction networks steer the fate of cancer cells during oncolytic virus infection. My work integrates virology, cell biology, and therapeutic context to map the molecular decisions that enable viral oncolysis, stress responses, and anti-tumor effects. I aim to translate these mechanistic insights into strategies that improve oncolytic virotherapy and immuno-oncology outcomes.
Current Focus
Oncolytic virus–cancer interactions
Nationality
India 🇮🇳
Latest event
Education
Academic foundations across biotechnology and immuno-oncology.
Integrated B.Tech + M.Tech in Biotechnology
Bhubaneswar, India 🇮🇳
Research Experience
Translational virology, immunology, and oncolytic virotherapy.
- Supervisor: Prof. Marcelo Ehrlich
- Thesis title: Signal transduction crossroads as fate determinants of the interactions of oncolytic viruses and cancer cells
Jan 2017 – Jul 2019
Master Student, Cellular and Molecular Virology Lab
Translational Health Science and Technology Institute
Faridabad, India 🇮🇳
- Supervisor: Dr. Guruprasad Medigeshi
- Master’s Dissertation: Cloning and purification of Respiratory Syncytial Virus NS1 protein to identify interacting proteins
Oct 2017 – Feb 2019
Junior Research Fellow, Bioassay Lab
Translational Health Science and Technology Institute
Faridabad, India 🇮🇳
- Supervisors: Dr. Guruprasad Medigeshi and Dr. Gagandeep Kang
- Project: Indian Impact Studies; New State Roll Out
- Supervisor: Dr. Triveni Krishnan
- Clinical diagnostics for acute watery diarrhea and HIV cases using molecular virology techniques
- Supervisor: Dr. Susruta Sen
Selected Publications
Peer-reviewed work in oncolytic virotherapy and cell fate biology.
cJun-N-terminal kinase activity and mitosis perturbation drive the 2-methoxyestradiol-mediated enhancement of viral oncolysis by Epizootic Hemorrhagic Disease Virus-Tel Aviv University
Scientific Reports, 2025
Impact Factor: 3.9 (2024)doi:10.1038/s41598-025-08687-8Nuclear Morphology-Based Assessment of Cell Fates Induced by a Microtubule Targeting Agent as a Single Treatment or Combined with an Oncolytic Virus
Methods in Molecular Biology, Springer Nature, 2025
doi:10.1007/978-1-0716-4542-0_8Arrest and Attack: Microtubule-Targeting Agents and Oncolytic Viruses Employ Complementary Mechanisms to Enhance Anti-Tumor Therapy Efficacy
Genes (Basel), 2024
Impact Factor: 2.8 (2024)doi:10.3390/genes15091193Skills
Laboratory, analytical, and scientific communication expertise.
Immunology & Virology
- Flow cytometry, immunocytochemistry
- Virus propagation and infection
- Plaque and neutralization assays
- Handling patient serum samples for immunological assays
- BSL-2 handling of viruses
• EHDV-TAU, VSV-DM51, HSV-1, JEV
• Additional: Dengue (DenV1–4), RSV, rotavirus, WNV
Molecular Biology
- Western blotting, RT-PCR, cloning, transfection
- Agarose gel electrophoresis, SDS-PAGE
Cell Culture & In Vivo Models
- Mammalian cell maintenance
- Cell-based assays
- Tumour and oncolytic virotherapy models (syngeneic melanoma, prostate cancer xenografts)
Imaging & Analysis
- Epifluorescence and confocal microscopy
- Data organisation and statistical analysis
- Basic bioinformatics
Scientific Communication
- Scientific writing, presentation, and documentation
Academic Engagements
Conference presentations and scholarly visibility.
30th European Cell Death Organisation Conference
Belval, Luxembourg 🇱🇺
Poster
2nd Retreat of Shmunis School of Biomedicine and Cancer Research
Tel Aviv-Yafo, Israel 🇮🇱
Flash Talk and Poster
1st Retreat of Shmunis School of Biomedicine and Cancer Research
Tel Aviv-Yafo, Israel 🇮🇱
Poster
Grants & Funding
Competitive awards supporting doctoral training and travel.
Shmunis Travel Grant and Tel Aviv University Travel Grant
Conference travel support
S Daniel Abraham Institute for Molecular Virology
Tel Aviv University funding for doctoral education
Shmunis Excellence Scholarship
Awarded in 2022 and 2023
TATA Trust–Tel Aviv University PhD Scholarship
Funding for doctoral education following a competitive open call
Trainings & Certifications
Specialized training for animal research and biosafety handling.